What is multilevel degenerative disc disease?

Picture of Dr. Pasquale X. Montesano
Dr. Pasquale X. Montesano

Principal Orthopedic Spine surgeon at Montesano Spine & Sport.

degenerative disc disease

Multilevel degenerative disc disease (DDD) is a condition in which two or more intervertebral discs in the spine show signs of wear and tear or degeneration. It most commonly affects the lumbar (lower back) and cervical (neck) spine.


What Happens in DDD?

Discs between vertebrae lose their normal:

  • Height
  • Hydration
  • Elasticity

This can lead to:

  • Disc bulges or herniations
  • Reduced space between vertebrae
  • Bone spurs (osteophytes)
  • Facet joint arthritis
  • Nerve compression

Common Locations

  • Cervical spine (neck): C4-C5, C5-C6, C6-C7
  • Lumbar spine (lower back): L3-L4, L4-L5, L5-S1

Symptoms May Include

  • Chronic or intermittent neck or back pain
  • Stiffness or reduced range of motion
  • Radiating pain, numbness, or weakness in arms or legs (if nerves are compressed)
  • Pain worsens with sitting, bending, lifting, or twisting

Causes & Risk Factors

  • Aging (natural disc dehydration)
  • Genetics
  • Repetitive strain or injury
  • Poor posture
  • Smoking (slows disc healing)
  • Obesity

Treatment Options

Non-Surgical

  • Physical therapy
  • Anti-inflammatory meds
  • Epidural or facet joint injections
  • Postural training and ergonomics
  • Laser therapy or chiropractic care

Surgical (if severe)

  • Spinal fusion
  • Artificial disc replacement
  • Laminectomy or discectomy